Papilomatose de laringe
DOI:
https://doi.org/10.22491/2357-9730.125224Keywords:
Laryngeal papillomatosis, human papilloma virus (HPV), carbon dioxide laser, adjuvant treatmentAbstract
Laryngeal papillomatosis is the most frequent benign neoplasm of the larynx, occurring in children and adults. It is caused by the human papilloma virus, especially types 6 and 11. The clinical course is unpredictable and recurrence is frequent in children. There have been reports of association between this disease and tracheobronchial tree and squamous cell carcinoma of the larynx. Papillomatosis is probably one of the
factors that can predispose a patient to the development of cancer, similarly to alcohol, tobacco, and radiation exposure.Treatment aims at maintaining airway patency and speech. Surgery with carbon dioxide laser is able to achieve this objective, however, without preventing recidivation. The low rates of surgical cure have been stimulating new research with chemotherapics. Unfortunately these have not been successful. Their main purpose is to reduce the extension of the disease and rates of recidivation, slowing down papilloma growth.The present study reviews pathophysiology, the clinical presentation and treatment aspects .
Downloads
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
