The meaning of local recurrence in conservative treatment of breast cancer

Authors

  • Jorge V. Biazús
  • Carlos H. Menke
  • José A. Cavalheiro
  • Nilton L. Xavier
  • Rodrigo Cericatto
  • Ana C. Bittelbrun
  • Eliane G. Rabin

DOI:

https://doi.org/10.22491/2357-9730.125890

Keywords:

Breast cancer, local recurrence, mastectomy, conservative surgery, prognostic factors

Abstract

Conservative surgery associated with radiotherapy has shown overall survival rates similar to those of radical mastectomy, despite a great deal of variation in the rate of local recurrence according to different surgical approach. The free margins and absence of radiotherapy have a significant impact on local recurrence. In this review, factors associated with positive or negative outcomes are reviewed , as well diagnosis and treatment difficulties. At the moment, the best predictive factor for outcome of local recurrence is disease extension at initial diagnosis and treatment. Despite the fact that local recurrence after mastectomy is associated with systemic disease, patients with recurrence after BCT seem to have a more positive prognosis.

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Published

2022-07-18

How to Cite

1.
V. Biazús J, H. Menke C, A. Cavalheiro J, L. Xavier N, Cericatto R, C. Bittelbrun A, et al. The meaning of local recurrence in conservative treatment of breast cancer. Clin Biomed Res [Internet]. 2022 Jul. 18 [cited 2026 Aug. 3];21(2). Available from: https://seer.ufrgs.br/index.php/hcpa/article/view/125890

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