Severe acute pancreatitis in a critical care unit
a 10-year evaluation
DOI:
https://doi.org/10.22491/2357-9730.125240Keywords:
Severe acute pancreatitis, prognostic signs, multiple organ failure, intensive careAbstract
OBJECTIVE: To evaluate etiology, complications, treatment, hospital and intensive care unit stay and mortality in all patients hospitalized in the intensive care unit of Hospital de Clínicas de Porto Alegre with acute pancreatitis, from January 1st, 1990 to December 31st, 1999.
MATERIALS AND METHODS: We performed a historical cohort study with 57 patients, 37% female and 63% male, with an age average of 48±17 years. Patients were classified in two groups – survivors (n=26, 45.6%) and non-survivors (n=31, 54.4%) – and compared considering hospital and intensive care unit stay, Ranson’s and modified Glasgow’s signs, APACHE II (acute physiology and chronic health evaluation), organ failure, surgery, parenteral nutrition and antibiotics.
RESULTS: The most common causes of severe acute pancreatitis were alcohol (37%) and gallstones (31%). Mortality was 54.4 %. Hospital stays were longer for survivors than for non-survivors. Non-survivors presented more organ failures (respiratory, renal
and cardiovascular failures) and more Ranson’s and modified Glasgow’s signs than survivors. Other parameters were similar in both groups.
CONCLUSIONS: In order to better evaluate the reasons for the high rate of mortality identified in the present group in the studied period it would be necessary to perform a prospective study with stronger control of the interfering factors, including an evaluation of the cases of severe acute pancreatitis that are not admitted in the intensive care unit.
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