Vancomycin resistant enterococcus spp (VRE): follow up during 9 years in a tertiary teaching hospital in southern Brazil

Autores

  • Ana Maria Sandri Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul
  • Geórgia Lopes da Silva Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul
  • Sílvia Pedroso Tavares Soares Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul
  • Fabiano Ramos Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul
  • Luciana Ruschel de Alcântara Secretaria Municipal da Saúde de Santa Cruz do Sul
  • Larissa Lutz Hospital de Clínicas de Porto Alegre
  • Afonso Luís Barth Hospital de Clínicas de Porto Alegre Universidade Federal do Rio Grande do Sul

Palavras-chave:

Vancomycin-resistant Enterococcus, VRE, outbreak, surveillance.

Resumo

Introduction: Infection with vancomycin-resistant Enterococcus spp (VRE) has been a worldwide problem since mid 1980's and, in Brazil, since 1996. This study was conducted to evaluate the experience with VRE in our institution.

Methods: A prospective cohort study from 2000 to 2009 was conducted at Hospital São Lucas da PUCRS. All hospitalized patients with VRE positive culture were included and followed from their diagnosis until they were negative for VRE or their discharge. Only the first admission for each VRE positive patient was included. Pulsed field gel electrophoresis (PFGE) was performed to determine how VRE had spread.

Results: A total of 315 cases of VRE were identified, 224 of which were isolated from rectal swabs. Vancomycin-resistant/ampicilin susceptible Enterococcus faecalis were identified in 312 isolates. PFGE was performed in 47 VRE isolates that presented an indistinguishable migratory profile. The median length of hospital stay and length of stay before VRE isolation were 46 days and 21 days, respectively; 52% of the patients were aged 60 and above. The annual distribution of the new VRE cases showed a clear decrease from 2000 to 2009.

Discussion: This study shows a substantial VRE colonization (71%) with a homogenous pattern that emphasizes its transversal spread. Predominance of E. faecalis differs from the literature which largely describes a higher prevalence of vancomycin-resistant Enterococcus faecium . The follow up of VRE during 9 years in our institution highlighted the importance of continuous surveillance to prevent outbreaks in our hospital.

 

Downloads

Não há dados estatísticos.

Biografia do Autor

Ana Maria Sandri, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul

Infectious Diseases Service

MD; PhD

Geórgia Lopes da Silva, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul

Infection Control Service

Nurse

Sílvia Pedroso Tavares Soares, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul

Infection Control Service

Nurse

Fabiano Ramos, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul

Infectious Diseases Service; Head

Infection Control Service; Head

MD

Luciana Ruschel de Alcântara, Secretaria Municipal da Saúde de Santa Cruz do Sul

Epidemiological Surveillance

Nurse; Master

Larissa Lutz, Hospital de Clínicas de Porto Alegre

Microbiology Unit of the Department of Pathology

Pharmacist-Biochemist

Pos-Doc 

Afonso Luís Barth, Hospital de Clínicas de Porto Alegre Universidade Federal do Rio Grande do Sul

Biomedical Research Unit of the Department of Pathology; Coordinator

Associated Professor IV

Pharmacist-Biochemist

PhD

Downloads

Publicado

2015-01-05

Como Citar

1.
Sandri AM, Lopes da Silva G, Pedroso Tavares Soares S, Ramos F, Ruschel de Alcântara L, Lutz L, Barth AL. Vancomycin resistant enterococcus spp (VRE): follow up during 9 years in a tertiary teaching hospital in southern Brazil. Clin Biomed Res [Internet]. 5º de janeiro de 2015 [citado 4º de dezembro de 2022];34(4). Disponível em: https://seer.ufrgs.br/index.php/hcpa/article/view/50891

Edição

Seção

Artigos Originais

Artigos mais lidos pelo mesmo(s) autor(es)