Losartan-Induced Acute Interstitial Nephritis

Letícia Schwerz Weinert, Cristina Bergmann Triches, Cristiane Bauermann Leitão, Diego Miltersteiner, Cezar Amauri Ribeiro da Costa, Antônio Balbinotto, Sandra Pinho Silveiro, Jorge Luiz Gross

Abstract


Acute interstitial nephritis is an important cause of acute renal failure. The majority of cases results from exposure to drugs. How-ever imune-mediated injury and infection are common causes. The angiotensin-converting enzyme inhibitors have been implicated as possible etiologic agents, but we could not find previous data of acute intestitial nephritis associated with losartan exposure. We report a case of acute renal failure after losartan exposure, in a patient with diabetic nephropathy. The final diagnosis was confirmed by renal biopsy: acute interstitial nephritis.



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ISSN: 2357-9730 

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