Losartan-Induced Acute Interstitial Nephritis

Authors

  • Letícia Schwerz Weinert HCPA/Endocrinologia
  • Cristina Bergmann Triches HCPA/Endocrinologia
  • Cristiane Bauermann Leitão HCPA/Endocrinologia
  • Diego Miltersteiner HCPA
  • Cezar Amauri Ribeiro da Costa HCPA/Nefrologia
  • Antônio Balbinotto
  • Sandra Pinho Silveiro HCPA
  • Jorge Luiz Gross UFRGS/HCPA

DOI:

https://doi.org/10.22491/2357-9730.463

Abstract

Acute interstitial nephritis is an important cause of acute renal failure. The majority of cases results from exposure to drugs. How-ever imune-mediated injury and infection are common causes. The angiotensin-converting enzyme inhibitors have been implicated as possible etiologic agents, but we could not find previous data of acute intestitial nephritis associated with losartan exposure. We report a case of acute renal failure after losartan exposure, in a patient with diabetic nephropathy. The final diagnosis was confirmed by renal biopsy: acute interstitial nephritis.

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Author Biographies

Letícia Schwerz Weinert, HCPA/Endocrinologia

Médica Residente do Serviço de Endocrinologia do HCPA

Cristiane Bauermann Leitão, HCPA/Endocrinologia

Médica contratada do Serviço de Endocrinologia do HCPA

Sandra Pinho Silveiro, HCPA

Profa. Adjunta do Departamento de Medicina Interna, UFRGS Serviço de Endocrinologia

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Published

2007-07-03

How to Cite

1.
Weinert LS, Triches CB, Leitão CB, Miltersteiner D, Costa CAR da, Balbinotto A, et al. Losartan-Induced Acute Interstitial Nephritis. Clin Biomed Res [Internet]. 2007 Jul. 3 [cited 2026 Aug. 3];27(1). Available from: https://seer.ufrgs.br/index.php/hcpa/article/view/463

Issue

Vol. 27 No. 1 (2007): Revista HCPA

Section

Case Report

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