Impacts of SARS-COV-2 infection on pregnancy and the neonatal period: an integrative literature review
DOI:
https://doi.org/10.22491/2357-9730.144870Keywords:
Coronavirus, Pregnancy complications, Pregnancy, Prematurity, Preterm newbornAbstract
This is an integrative review with the objective of analyzing the available scientific evidence on the impacts of SARS-CoV-2 infection during pregnancy and the neonatal period. The article search was conducted in the PUBMED and Lilacs databases, using the descriptors “Maternal SARS-CoV-2 infection” and “prematurity”. The inclusion criteria were observational study articles, published in Portuguese or English, freely accessible, full-text, and published within the last three years. Eleven articles were included in the review. The majority of pregnant women contracted the infection in the third trimester, presenting as asymptomatic or with mild symptoms. The vertical transmission rate ranged from no positive cases to 13%. Most of the births were full-term; however, the rate of preterm births ranged from 9% to 37%. Most newborns had adequate birth weight and Apgar scores at both the 1st and 5th minutes. It can be concluded that most COVID-19 infections in pregnant women occur during the third trimester and are asymptomatic or present with mild symptoms. Maternal infection does not seem to interfere with most neonatal variables, although a higher rate of prematurity than global data suggests is observed.
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Copyright (c) 2025 Maria Eduarda Lemos de Souza, Myrcea de Souza Nunes Dellalibera, Carolina Caruccio Montanari, Martina Madalena Pedroso
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