ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats

Autores

  • Gustavo Alfredo Ochs de Muñoz Hospital de Clínicas de Porto Alegre
  • Nelson Alexandre Kretzmann
  • Mónica Luján López
  • Carlos Oscar Kieling
  • Carolina Uribe-Cruz
  • Luciano Basso da Silva
  • Alessandro Bersch Osvaldt
  • Ursula da Silveira Matte

Palavras-chave:

MAP Kinase Signaling System, stem cells, acute liver failure

Resumo

We investigated the influence of bone marrow cells upon activation of ERK ½ in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation.

Keywords: MAP Kinase Signaling System; stem cells; acute liver failure

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Publicado

2017-01-17

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1.
Ochs de Muñoz GA, Kretzmann NA, López ML, Kieling CO, Uribe-Cruz C, da Silva LB, Osvaldt AB, Matte U da S. ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats. Clin Biomed Res [Internet]. 17º de janeiro de 2017 [citado 7º de dezembro de 2022];36(4). Disponível em: https://seer.ufrgs.br/index.php/hcpa/article/view/68336

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