A complete study of Doxazosin characterization
DOI:
https://doi.org/10.22456/2527-2616.73960Keywords:
doxazosin, NMR, FT-IR, signals assignmentAbstract
Doxazosin is an important drug used to treat hypertension and prostatic hyperplasia. An enantiomeric (R)/(S) doxazosin
mesylate mixture was complete characterized by NMR and additionally FT-IR spectroscopy techniques. Different NMR
experiments were performed, such as APT, HSQC, and HMBC in order to confirm the NMR signals assignments. All the
hydrogens and most of carbons atoms were assigned. In this context, the results reported here, consists in important
information for identification and quality control of doxazosin mesylate.
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