SÍNDROME DA LISE TUMORAL

Authors

Caroline Rech Serviço de Medicina Interna, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brasil.
Elvino Barros Serviço de Nefrologia, HCPA, Porto Alegre, RS, Brasil.

DOI:

https://doi.org/10.22491/2357-9730.99780

Keywords:

Lise tumoral, hiperuricemia, doenças hematológicas, insuficiência renal.

Abstract

A síndrome da lise tumoral é caracterizada por complicações metabólicas e desenvolvimento de insuficiência renal aguda, em geral ocorrendo em acientes com neoplasias linfoproliferativas e após o início do tratamento quimioterápico. A hiperuricemia é o distúrbio metabólico mais característico, ocorrendo também hiperfosfatemia, hipocalcemia e hipercalemia. A insuficiência renal é decorrente principalmente da deposição de urato nos túbulos renais. Hidratação vigorosa e administração de alopurinol constituem o manejo principal da síndrome. Identificação precoce e instituição de medidas preventivas são importantes para que se evite o desenvolvimento de dano renal.
Unitermos: Lise tumoral, hiperuricemia, doenças hematológicas, insuficiência renal.

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Published

2020-01-29

How to Cite

1.

Rech C, Barros E. SÍNDROME DA LISE TUMORAL. Clin Biomed Res [Internet]. 2020 Jan. 29 [cited 2026 Aug. 11];26(3). Available from: https://seer.ufrgs.br/index.php/hcpa/article/view/99780

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Issue

Vol. 26 No. 3 (2006): Revista HCPA

Section

Review Articles

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