Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia

correlation of histopathological findings of breast biopsy and surgery

Authors

  • Henrique A. P. Pasqualette
  • Paulo M. S. Pereira
  • Maria J. G. Calas
  • Maria V. P. Dutra
  • Rosana de Castro
  • Valeska Caldoncelli
  • Vânia R. Manoel

DOI:

https://doi.org/10.22491/2357-9730.125725

Keywords:

Breast biopsy, breast neoplasm, diagnosis, breast surgery

Abstract

OBJECTIVE: To compare the histopathological findings of carcinoma and atypical hyperplasia obtained with breast biopsy and the respective surgical procedures.
MATERIAL AND METHODS: 527 breast biopsies were carried out at our services within an 18-month period. Out of these biopsies, 118 were diagnosed as carcinoma in situ or invasive carcinoma and atypical hyperplasia. Diagnosis was obtained with digital stereotactic breast biopsy. Patients presented asymptomatic, had subclinical lesions on mammographic screening, averaged 55 years of age, and were, in their majority, postmenopausal women.
RESULTS: Out of the 118 patients who fulfilled our study criteria, we were able to establish a comparison with the histopathological findings of surgical biopsy in 73 cases (61,9%). There was a loss of follow up in 45 cases (38,1 %). The histopathological findings were compatible with those of breast biopsy in 60 cases (82%), both in relation
to the type and histopathological grade of the lesion.
CONCLUSIONS: Breast biopsy represents an important alternative to surgical biopsy for the diagnosis of nonpalpable breast lesions. It is a rapid, easy to operate methodthat provides optimal results. In addition, its results presented a good rate of agreement with the histopathological findings of surgical biopsy. The quality of the collected material was considered satisfactory for the purpose of diagnosis. 

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Published

2022-07-18

How to Cite

1.
A. P. Pasqualette H, M. S. Pereira P, J. G. Calas M, V. P. Dutra M, de Castro R, Caldoncelli V, et al. Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery. Clin Biomed Res [Internet]. 2022 Jul. 18 [cited 2026 Aug. 3];21(2). Available from: https://seer.ufrgs.br/index.php/hcpa/article/view/125725

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Original Articles

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