Histopathological differences between genders in patients with oral squamous cell carcinoma

Autores

  • Fábio Muradás Girardi Universidade de Santa Cruz do Sul
  • Giulia Rubin Fuga School of Medicine, Universidade de Santa Cruz do Sul (UNISC). Santa Cruz do Sul, RS, Brazil.
  • Tássia Callai School of Medicine, Universidade de Santa Cruz do Sul (UNISC). Santa Cruz do Sul, RS, Brazil.
  • Marina Fernandes Bianchi School of Medicine, Universidade de Santa Cruz do Sul (UNISC). Santa Cruz do Sul, RS, Brazil.

Palavras-chave:

Oral neoplasms, carcinoma, squamous cell, prognosis

Resumo

Introduction: Oral cancer ranks fifth among the most frequent malignant tumors in men in Brazil. The incidence of this tumor among women has grown. It is still controversial whether gender can influence the outcome or the prognostic features of the disease.

Objectives: To compare the histopathological features of oral squamous cell carcinomas between genders among patients undergoing surgical treatment in an oncological hospital of southern Brazil.

Methods: Between 2007 and 2011, 404 patients underwent resection of malignant tumors of the oral cavity in the head and neck department of this institution. A subgroup of 209 previously untreated oral cavity squamous cell carcinoma cases was selected for comparative analysis.

Results: In total, 68 participants were women and 141 were men. The tongue was the most common subsite in both genders. Men presented lower mean age and women presented tumors with smaller depth of invasion. Although among women it was observed a trend towards tumors with less aggressive characteristics, no other variable showed statistically significance.

Conclusion: Women with oral tumors tend to present more superficial primary tumors and at a later age.

Keywords: Oral neoplasms; carcinoma; squamous cell; prognosis

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Biografia do Autor

Fábio Muradás Girardi, Universidade de Santa Cruz do Sul

Estudante de Medicina da Universidade de Santa Cruz do Sul

Giulia Rubin Fuga, School of Medicine, Universidade de Santa Cruz do Sul (UNISC). Santa Cruz do Sul, RS, Brazil.

Estudante de Medicina da Universidade de Santa Cruz do Sul

Tássia Callai, School of Medicine, Universidade de Santa Cruz do Sul (UNISC). Santa Cruz do Sul, RS, Brazil.

Estudante de Medicina da Universidade de Santa Cruz do Sul

Marina Fernandes Bianchi, School of Medicine, Universidade de Santa Cruz do Sul (UNISC). Santa Cruz do Sul, RS, Brazil.

Estudante de Medicina da Universidade de Santa Cruz do Sul

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Publicado

2017-09-29

Como Citar

1.
Muradás Girardi F, Rubin Fuga G, Callai T, Fernandes Bianchi M. Histopathological differences between genders in patients with oral squamous cell carcinoma. Clin Biomed Res [Internet]. 29º de setembro de 2017 [citado 29º de setembro de 2022];37(3). Disponível em: https://seer.ufrgs.br/index.php/hcpa/article/view/72986

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