Prevalence of red blood cell alloimmunization in multiply transfused patients

Autores

  • Fernanda Marcante Carlotto University Of Passo Fundo http://orcid.org/0000-0003-1074-1040
  • Bruna Schmitt Puhl University of Passo Fundo
  • Antonio Albuquerque Beninca University of Passo Fundo
  • Bruna Accorsi Machado Hematology and e hemotherapy's departament , Hospital São Vicente de Paulo. Passo Fundo, RS, Brazil
  • Cristiane Rodrigues de Araujo Hematology and e hemotherapy's departament , Hospital São Vicente de Paulo. Passo Fundo, RS, Brazil

Palavras-chave:

Red blood cells, erythrocytes, alloimmunization, alloantibodies, transfusion, elderly

Resumo

Introduction: To analyze the prevalence of alloantibodies in multiply transfused patients. Methods: This study was a retrospective, exploratory and descriptive study with a quantitative approach. The study sample comprised 185 patients transfused at a referral service in the city of Passo Fundo, Rio Grande do Sul, from January 2016 to February 2018. Results: Overall, the antibodies identified were as follows: anti-E in 47 patients (18%), anti-D and anti-K in 28 patients each (11%), anti-C in 21 patients (8.1%), and inconclusive antibody results in 23 patients (8.9%). Females were a majority (55.7%), mean age was 48.8 years and mean quantity of blood transfused was 7.2 bags. Cardiovascular disorders were the most common comorbidities, in 39 patients (21.2%), followed by oncological disorders, in 38 patients (18.4%). Conclusion: Alloimmunization is an important and frequent clinical condition that increases the risk of hemolytic reactions and is associated with significant patient morbidity and mortality.

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Publicado

2021-02-03

Como Citar

1.
Carlotto FM, Puhl BS, Beninca AA, Machado BA, de Araujo CR. Prevalence of red blood cell alloimmunization in multiply transfused patients. Clin Biomed Res [Internet]. 3º de fevereiro de 2021 [citado 27º de setembro de 2022];40(2). Disponível em: https://seer.ufrgs.br/index.php/hcpa/article/view/102374

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