Feasibility study of antiseptic gel formulations containing essential oils of Cymbopogon citratus (DC.) stapf. and of Caryophyllus aromaticus L.
DOI:
https://doi.org/10.22456/2527-2616.77118Keywords:
Essential oil, Gel formulation, MIC, ViabilityAbstract
In recent years we have seen an increase in the pursuit of products and active compounds of natural origin by the pharmaceutical industry. Additionally, there is a need for creation of new market products such as antiseptics, used to prevent or decrease risk of infection by inhibiting the proliferation of microorganisms. The objective of this study was to produce two antiseptic gels incorporating into each of them, individually, lemon grass (Cimbopogon citratos (DC.) Stapf.) essential oil and clove (Caryophillus aromaticus L.) essential oil, subsequently evaluating antimicrobial activity by minimum inhibitory concentration (MIC) test. Oils and gels were tested in parallel and showed a similar profile that can be observed in the inhibition concentration. This was a preliminary study that merits further investigation, which may include stability testing and evaluation of lower concentrations of oils incorporated into the gel base.
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