Anti-Candida activity of terpenes from Salvia ovalifolia, S. procurrens and S. uliginosa, native to South Brazil

Cristiano da Silva  Sousa; Letícia Mezzomo; Juliana Caroline Butzge; Gabriela de Carvalho Meirelles; Sérgio Augusto de Loreto Bordignon; Gilsane Lino von Poser; Miriam Anders Apel

doi:10.22456/2527-2616.128293

Authors

Cristiano da Silva Sousa Programa de Pós‐Graduação em Ciências Farmacêuticas, Faculdade de Farmácia - Universidade Federal do Rio Grande do Sul (UFRGS)
Letícia Mezzomo Programa de Pós‐Graduação em Ciências Farmacêuticas, Faculdade de Farmácia - Universidade Federal do Rio Grande do Sul (UFRGS)
Juliana Caroline Butzge Programa de Pós‐Graduação em Ciências Farmacêuticas, Faculdade de Farmácia - Universidade Federal do Rio Grande do Sul (UFRGS)
Gabriela de Carvalho Meirelles Programa de Pós‐Graduação em Ciências Farmacêuticas, Faculdade de Farmácia - Universidade Federal do Rio Grande do Sul (UFRGS)
Sérgio Augusto de Loreto Bordignon Postgraduate Program of Environmental Impact Assessment - UNILASALLE University
Gilsane Lino von Poser Programa de Pós‐Graduação em Ciências Farmacêuticas, Faculdade de Farmácia - Universidade Federal do Rio Grande do Sul (UFRGS)
Miriam Anders Apel Programa de Pós‐Graduação em Ciências Farmacêuticas, Faculdade de Farmácia - Universidade Federal do Rio Grande do Sul (UFRGS)

DOI:

https://doi.org/10.22456/2527-2616.128293

Keywords:

Salvia, Lamiaceae, terpenes, HPLC analysis, Candida

Abstract

The essential oils of Salvia ovalifolia, S. procurrens and S. uliginosa were obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. The three species displayed very low amounts of essential oils, consisting of a few sesquiterpenes, and aliphatic compounds such as aldehydes and long-chain fatty acids. From the leaves of S. uliginosa, an exudate was obtained which presented the diterpene icetexone as the major component. The exudate and icetexone were evaluated for the activity against Candida species, both showing inhibition of fungal growth.

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