DANOS MOLECULARES EM PACIENTES URÊMICOS SUBMETIDOS À HEMODIÁLISE
DOI:
https://doi.org/10.22491/2357-9730.99777Keywords:
DNA mitocondrial, hemodiálise, danos moleculares, insuficiência renal crônicaAbstract
Os efeitos tóxicos decorrentes do estado urêmico e do tratamento através de hemodiálise vêm sendo sugeridos como responsáveis por danos no DNA em pacientes com insuficiência renal crônica. Dessa forma, muitos trabalhos têm desenvolvido marcadores capazes de identificar esses danos através da análise cromossômica, teste de micronúcleos, teste do cometa, teste eletroquímico e,
mais recentemente, análise do DNA mitocondrial. Considerando que esses danos podem aumentar a incidência de câncer, mais estudos devem continuar sendo desenvolvidos nesse sentido.
Unitermos: DNA mitocondrial, hemodiálise, danos moleculares, insuficiência renal crônica
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