Use of MALDI-TOF MS in diagnostic microbiology for identification of species that conventional methods usually fail to identify
DOI:
https://doi.org/10.22491/2357-9730.90933Keywords:
Non-tuberculous Mycobacteria, Mycobacterium abscessus, Bacterial infections, Actinotignum schaalii, Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAbstract
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used in clinical diagnostic laboratories for the identification of microorganisms. It has a relevant advantage compared to other methods in terms of speed to provide results, being an alternative for addressing restrictions in clinical diagnosis as it may replace or complement existing identification techniques. This is especially important because some rare microorganisms would be identified only by higher cost techniques which are not widely available, such as genetic sequencing. Thus, the present paper reports two cases in which uncommon microorganisms were identified effectively and quickly.
Keywords: Non-tuberculous Mycobacteria; Mycobacterium abscessus; Bacterial infections; Actinotignum schaalii; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
