Impact of COVID-19 on in-hospital mortality associated with pulmonary thromboembolism
DOI:
https://doi.org/10.22491/2357-9730.149132Keywords:
Pulmonary embolism, Venous thromboembolism, Mortality, COVID19Abstract
Objectives: To evaluate the mortality rate associated with pulmonary thromboembolism (PTE) in patients who required hospital treatment and to verify the impact of the association with SARS-COV 2 infection on prognosis. Methods: This was a retrospective study that included all patients diagnosed with PTE, identified through the review of all contrast-enhanced chest CT scans performed at the institution over a period of 5 years. A descriptive analysis was carried out on the demographic and clinical characteristics, mortality and impact of the association with SARS-COV-2 infection. Results: A total of 533 cases of PTE were identified by the presence of a filling defect in a branch of the pulmonary artery on CT, performed on average 5.4 days after hospitalization. In-hospital mortality from any cause in the groups without and with SARS-CoV-2 infection was 19.1% and 21.1%, respectively, and there was no difference related to gender, ethnicity, age, or presence of COVID-19. The relative risk (RR) for death in the population with COVID-19 was 1.09 (95% CI 0.76-1.56; p>0.05), and the presence of neoplasia was associated with higher mortality (RR= 1.94; 95% CI 1.38-2.74; p<0.0001). Conclusions: The overall in-hospital mortality associated with pulmonary thromboembolism was similar to that reported in the literature for patients stratified as high risk, and there was no difference in relation to SARS-CoV-2 infection, but concomitant neoplasia was associated with higher mortality.
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Copyright (c) 2026 Gabriela Ponte de Mattos, Aline Pizzato Saldanha de Souza, Marcela Silva Fructos, Maria Eduarda Meirelles Marchese, Carolina Borchardt Heidtmann, Waldo Luis Leite Dias de Mattos
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