Implementation of a Program to Prevent Possible Drug-Food Interactions in Adult Patients Hospitalized in Clinical and Surgical Cares of a University Hospital

Authors

  • Lucas Magedanz UFRGS/Faculdade de Farmácia
  • Thalita Jacoby HCPA/Unidade de Assistência Farmacêutica
  • Daiandy da Silva HCPA/Unidade de Assistência Farmacêutica
  • Luciana dos Santos HCPA/Unidade de Assistência Farmacêutica
  • Jacqueline Martinbiancho HCPA/Unidade de Assistência Farmacêutica
  • Joice Zuckermann HCPA/Centro de Informações sobre Medicamentos

Keywords:

assistência farmacêutica, farmacovigilância, interação fármaco-alimento

Abstract

Drug-food interactions (DFI) are defined as alterations produced in the therapeutic effects of a medicine due to concomitant food ingestion. Objective: To identify possible with medical prescriptions for hospitalized patients in the IFA “Hospital de Clínicas de Porto Alegre” (HCPA), and guide the clinical staff about the appropriate timing of administration of medicines. Methods: The study examined, between February and July 2006, 2645 prescriptions for adult patients hospitalized in medical and surgical units of HCPA, who received oral diet. Results: We found that 54.5% (1,442) prescriptions had potential DFI. In such cases, the teams were receiving care by a notification in medical records, information about the medicines they needed a fasting interval, to ensure their maximum bioavailability. Conclusions: The high incidence of prescription medicines containing possible to interact with food shows the need for a system offering, systematically, the orientations regarding the adequate administration of the medicines.

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Published

2009-04-30

How to Cite

1.
Magedanz L, Jacoby T, da Silva D, dos Santos L, Martinbiancho J, Zuckermann J. Implementation of a Program to Prevent Possible Drug-Food Interactions in Adult Patients Hospitalized in Clinical and Surgical Cares of a University Hospital. Clin Biomed Res [Internet]. 2009 Apr. 30 [cited 2025 May 2];29(1). Available from: https://seer.ufrgs.br/index.php/hcpa/article/view/5984

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Original Articles

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