Adjuvant systemic therapy for breast cancer
Keywords:
Chemotherapy, hormone therapy, systemic therapy, prognostic factorsAbstract
Since the 1970s, substantial progress has been made in the understanding of the biology of breast cancer, on diagnostic approaches, and in determination of risk factors. This progress has been associated with advancements in the efficacy of treatments. Currently, many patients are receiving treatments that used to be reserved for cases with metastases. Clinical, multi-centered trials carried out by different authors have allowed for a continuous reevaluation of the basis of knowledge and recommendations of adjuvant therapy. Breast cancer, in this sense, is now understood as a systemic disease, which corroborates the use of systemic therapy in early breast cancer.
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