Comparative evaluation of the toxicity of the all bond 2 dentin adhesive and the zinc oxide eugenol cement when implanted in the subcutaneous connective tissue of rats

Authors

  • Carlos Alberto de Souza Costa UNESP
  • Josimeri Hebling UNESP
  • Heron Fernando de Sousa Gonzaga UNESP
  • Carlos Benatti Neto UNESP
  • Luis Carlos Spolidório UNESP

DOI:

https://doi.org/10.22456/2177-0018.7826

Keywords:

Dentin adhesives, Biocompatible materials, Zinc oxide, Eugenol

Abstract

Apreliminary study of biocompatibility of dentin adhesive, All Bond 2 and Zinc oxide and Eugenol (ZOE) was realized after subcutaneous implantation in rats. The implants, poliethylene tubes filled with the dentin adhesives, were inserted into dorsal surgical pockets of 20 rats, and the animals sacrificed 7, 15, 30 and 60 days after. Serial sections of skin, stained with hematoxylin and eosin, showed in the first period (7 days) that All Bond 2 promoted a intense inflammatory reaction, moderate contact necrosis and collagen degradation. The ZOE promoted a slight reaction when compared with experimental group. During the experiment, the subcutaneous tissue presented tendency for healing, with organization of a fibrous capsule surronding the tubes. Althought for All Bond 2, into these fibrous tissue, was observed a mild mononuclear inflammatory cells. It was concluded that All Bond 2s the aceitable materials when implanted in subcutaneous tissue of rats.

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Author Biographies

Carlos Alberto de Souza Costa, UNESP

Professor Assistente do Departamento de Patologia da Faculdade de Odontologia de Araquara - UNESP

Josimeri Hebling, UNESP

Professor Assistente do Departamento de Clínica Infantil da Faculdade de Odontologia de Araquara - UNESP

Heron Fernando de Sousa Gonzaga, UNESP

Professor Assistente Doutor do Departamento de Patologia da Faculdade de Odontologia de Araquara - UNESP

Carlos Benatti Neto, UNESP

Professor Assistente Doutor do Departamento de Patologia da Faculdade de Odontologia de Araquara - UNESP

Luis Carlos Spolidório, UNESP

Professor Assistente do Departamento de Patologia da Faculdade de Odontologia de Araquara - UNESP

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Published

1996-01-01

How to Cite

Costa, C. A. de S., Hebling, J., Gonzaga, H. F. de S., Benatti Neto, C., & Spolidório, L. C. (1996). Comparative evaluation of the toxicity of the all bond 2 dentin adhesive and the zinc oxide eugenol cement when implanted in the subcutaneous connective tissue of rats. Revista Da Faculdade De Odontologia De Porto Alegre, 37(2), 3–6. https://doi.org/10.22456/2177-0018.7826

Issue

Vol. 37 No. 2 (1996)

Section

Original articles

License

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