Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil


  • Deborah Beltrami Gomez Universidade Federal do Rio Grande do Sul
  • Ivan Sereno Montenegro UFRGS
  • Guilherme Rezende Baade UFRGS
  • Paula Barros Terraciano UFRGS
  • Raquel de Almeida Schneider HCPA
  • Débora Helena Zanini Gotardi HCPA
  • Victória Furquim dos Santos Cardoso HCPA
  • Eduardo Pandolfi Passos UFRGS


Chlamydia trachomatis, Chlamydia infections, prevalence, Nucleic Acid Amplification Techniques, Infertility, female, Fluorescent Antibody Technique


Introduction: Chlamydia trachomatis (CT) is the most prevalent sexually transmitted bacterial infection, affecting mainly young, sexually active women. Untreated infection may lead to reproductive complications due to tubal damage. Infections during pregnancy may cause preterm labor, low birth weight, perinatal death, and neonatal conjunctivitis and pneumonia. There are few data on CT infection in Brazil. The aim of this study was to determine CT prevalence in infertile and pregnant women.

Methods: A cross-sectional study included 77 infertile and 60 asymptomatic pregnant women. First-void urine was tested for CT using PCR (Polymerase Chain Reaction). Blood samples were collected for CT IgG antibodies testing using indirect immunofluorescence. A questionnaire about medical, gynecological, and sexual history was completed by all participants.

Results: We found statistically similar prevalence of PCR and IgG antibodies between the groups. There was a 61% prevalence of CT IgG antibodies in infertile women and 56.7% in pregnant women. PCR was positive in only one (1.3%) infertile woman and in none pregnant women.

Conclusion: There is a high prevalence of CT IgG antibody in Brazilian pregnant and infertile women, but we found a low prevalence of positive PCR in the urine samples. CT antibodies were associated with sexual behavior and smoking.

Keywords: Chlamydia trachomatis, Chlamydia infections, prevalence, nucleic acid amplification techniques; infertility, female; fluorescent antibody technique


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Como Citar

Gomez DB, Montenegro IS, Baade GR, Terraciano PB, Schneider R de A, Gotardi DHZ, Cardoso VF dos S, Passos EP. Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil. Clin Biomed Res [Internet]. 21º de outubro de 2016 [citado 28º de setembro de 2023];36(3). Disponível em:



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