A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries

Authors

DOI:

https://doi.org/10.22456/2177-0018.130357

Keywords:

Root caries, Fluorides, topical, Cost-benefit analysis

Abstract

Aim: to evaluate the prognosis of root caries treatment with non-invasive methods, as well as to compare non-invasive therapies as viable alternatives for clinicians, indicating their cost-effectiveness. Literature review: Data collected were number of active lesions at baseline(BL) and in the last clinical assessment after follow-up(FL), and the follow-up period in months(P). The outcome was the monthly progression rate of the lesions that was calculated by (FL–BL)/P. A negative progression rate means the arrestment of the lesions. A cost-effectiveness rate was calculated. Results: From 596 titles retrieved in the search, 8 studies were included in a qualitative synthesis after assessed for eligibility. The monthly progression rate of lesions of home-based treatments (toothpastes, mouth rinses, supplemented milk intake) was an average of -0.79 (-3.68 to 2.3), while the office-based treatments (varnish, topic solutions) was 0.07 (-0.01 to 0.51), suggesting a better prognosis of the home-based treatments. The lowest monthly progression rate was -3.97 (toothpaste 5000ppm/F) while the highest was 2.31 (conventional toothpaste). The cost-effectiveness rate was better for treatments with toothpastes with 5000ppm/F (BRL21.78) when compared to mouthwashes (BRL579.47). Discussion: A better prognosis was found for toothpastes with a high fluoride concentration (5000ppm/F) compared to other therapies, as well as a better cost-effectiveness when compared to mouthwashes. Conclusion: Home-based therapies represented the highest rates of good prognosis for treating root caries lesions within the available scientific evidence. Although 5000ppm/F toothpastes have a very high cost for the Brazilian market, this treatment presented the highest cost-effectiveness when compared to mouthrinses (PROSPERO:CRD42019136035).

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Published

2023-07-20

How to Cite

de Resende Cussi, F. L. ., Poubel, D. L. do N., Lima, A. de A. de, Figueiredo, A. C. M. G., Stefani, C. M., Garcia, F. C. P., & Damé-Teixeira, N. (2023). A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries. Revista Da Faculdade De Odontologia De Porto Alegre, 64, e130357. https://doi.org/10.22456/2177-0018.130357

Issue

Vol. 64 (2023)

Section

Review articles

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Copyright (c) 2023 Fábio Luiz de Resende Cussi, Déborah Lousan do Nascimento Poubel, Adriano de Almeida de Lima, Ana Claudia Morais Godoy Figueiredo, Cristine Miron Stefani, Fernanda Cristina Pimentel Garcia, Nailê Damé-Teixeira

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