Immunologic aspects of dental caries

Authors

  • Leão Pereira PINTO UFRN
  • Lélia Maria Guedes QUEIROZ UFRN
  • Cassiano Francisco Weege NONAKA UFRN
  • George João Ferreira do NASCIMENTO UFRN

DOI:

https://doi.org/10.22456/2177-0018.7605

Keywords:

Dental caries, Immunology, Vaccine

Abstract

Significant advances on elaboration of vaccine against dental caries are result of several genetic and molecular investigations addressed to S. mutans and S. sobrinus and to the mechanism of immune host response. These investigations lead to the recognition not only of which are the best streptococcal vaccine antigen candidates, as well as more efficient immunogen routes, responsible for dicreasing bacterial colonization and, consequently, the number of carious lesions. The present paper makes a critical evaluation about up-to-date aspects related to the progression and limitations of principal types proposed as an anti-caries vaccine.

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Author Biographies

Leão Pereira PINTO, UFRN

Professor Doutor da Disciplina de Patologia Oral e do Programa de Pós-Graduação em Patologia Oral da Universidade Federal do Rio Grande do Norte (UFRN)

Lélia Maria Guedes QUEIROZ, UFRN

Professora Doutora da Disciplina de Patologia Oral e do Programa de Pós-Graduação em Patologia Oral da Universidade Federal do Rio Grande do Norte (UFRN)

Cassiano Francisco Weege NONAKA, UFRN

Aluno do Programa de Pós-Graduação em Patologia Oral da Universidade Federal do Rio Grande do Norte (UFRN)

George João Ferreira do NASCIMENTO, UFRN

Aluno do Programa de Pós-Graduação em Patologia Oral da Universidade Federal do Rio Grande do Norte (UFRN)

Published

2005-01-26

How to Cite

PINTO, L. P., QUEIROZ, L. M. G., NONAKA, C. F. W., & NASCIMENTO, G. J. F. do. (2005). Immunologic aspects of dental caries. Revista Da Faculdade De Odontologia De Porto Alegre, 46(1), 19–22. https://doi.org/10.22456/2177-0018.7605

Issue

Section

Original articles