Immunologic aspects of dental caries

Leão Pereira PINTO, Lélia Maria Guedes QUEIROZ, Cassiano Francisco Weege NONAKA, George João Ferreira do NASCIMENTO

Abstract


Significant advances on elaboration of vaccine against dental caries are result of several genetic and molecular investigations addressed to S. mutans and S. sobrinus and to the mechanism of immune host response. These investigations lead to the recognition not only of which are the best streptococcal vaccine antigen candidates, as well as more efficient immunogen routes, responsible for dicreasing bacterial colonization and, consequently, the number of carious lesions. The present paper makes a critical evaluation about up-to-date aspects related to the progression and limitations of principal types proposed as an anti-caries vaccine.

Keywords


Dental caries; Immunology; Vaccine



DOI: https://doi.org/10.22456/2177-0018.7605

Licença Creative Commons

e-ISSN 2177-0018 / ISSN 0566-1854.

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