Clinical and therapeutic approach to keratocystic odontogenic: an in-depth literature review

Natália da Silva Medeiros, Eduardo Madruga Lombardo, Fábio Luiz Dal Moro Maito, Cláiton Heitz

Abstract


Keratocystic odontogenic is an intraosseous benign tumor whose prevalence corresponds to 11% of cystic lesions of the maxilla and mandible. Objective: perform an organized review of the literature of a keratocystic odontogenic tumor. Material and Methods: a search of clinical case reports was performed through PubMed database under the following criteria: type of study (case report), in English, only studies in humans, no publication date limit. Results: the relevant data of 85 selected articles were registered. The data collection established that the Keratocystic odontogenic has a predilection for male patients, between the third and fourth decades of age. Commonly occurs in the jaw, preferably in posterior region. The most frequent initial clinical aspect was swelling. Regarding imaging aspects, features as a single or multiple radiolucent image, uni or multilocular. Histopathologic examination is essential for diagnosis. Enucleation was the therapeutic approach established in most cases. In cases of multiple lesions, the Gorlin-Goltz syndrome should be investigated. The follow-up time, the rate of recurrence and malignant transformation were variable. Final considerations: histopathological examination it is essential to stablish a definitive diagnosis of keratocystic odontogenic. The most appropriate therapeutic approach is enucleation associated with an adjuvant treatment. Periodic follow-up is mandatory given the high potential of recurrence of this type of lesion.

Keywords


Keratocysts; Odontogenic cysts; Keratocystic odontogenic tumor

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