The mechanisms of osteoclastic activity: literature review

Ângelo Barbosa Resende, Luciano Barreto Silva, Carolina dos Santos Guimarães, Rosana Maria Coelho Travassos, Ana Paula Veras Sobral

Abstract


Bone tissues are continually being remodeled depending on the organic situation, with hard tissue resorption and neoformation. Homeostasis and inflammatory conditions concerning bone may bring about the activation of hematopoietic cells with the ability to generate or dissolve bone matrix for a number of organic needs. The mechanisms used by osteoclasts to resorb hard tissues and the basic cell to cell interactions, with the participation of immune cells such as lymphocytes, along with other substances, as well as bone composition are described in this review.

Keywords


Bone tissue; T-lymphocytes; Bone matrix

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DOI: https://doi.org/10.22456/2177-0018.20517

Licença Creative Commons

e-ISSN 2177-0018 / ISSN 0566-1854.

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