Placental mesenchymal dysplasia and intrauterine fetal growth restriction with doppler velocimetry alterations - a case report

Paula Vendruscolo Tozatti, Ana Lúcia Letti Muller, Maria Teresa Viero Sanseverino, Jose Antonio de Azevedo Magalhães, Raquel Rivero, Rejane Gus


Placental mesenchymal dysplasia (PMD) is a rare placental abnormality. We report a case of PMD associated with intrauterine growth restriction (IUGR), which was diagnosed by an ultrasound scan during the second trimester of pregnancy. A 36-year-old primiparous woman with signs of placental chorioangioma was referred to our hospital at the 23th gestational week. An ultrasonography revealed a small-for-gestational-age fetus with a large multicystic placenta. A serial Doppler sonographic assessment of umbilical and uterine artery blood flow showed a compromised fetus. A female, small-for-gestational-age baby was delivered by c-section at 28 weeks, and PMD was histopathologically confirmed.


Placental mesenchymal dysplasia, intrauterine fetal growth restriction, placental vesicles, doppler velocimetry

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ISSN: 2357-9730



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