Tumor neuroendócrino em coração de cão: Relato de caso.

Autores

  • Acauã Belém Barreto Batista de Oliveira Autonomous Veterinarian, Rio de Janeiro, RJ, Brazil.
  • Carolina do Valle Aben-Athar Programa de Pós-Graduação em Medicina Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brazil. https://orcid.org/0000-0002-5461-5276
  • Mário dos Santos Filho Programa de Pós-Graduação em Medicina Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brazil. https://orcid.org/0000-0003-0295-2200
  • Alexandre José Rodrigues Bendas Departamento de Medicina e Cirurgia Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brazil. https://orcid.org/0000-0003-4320-9923
  • Sara Maria de Carvalho Suzano Escola de Veterinária, Universidade Castelo Branco, Rio de Janeiro, RJ, Brazil. https://orcid.org/0000-0001-9089-1211
  • Daniel de Almeida Balthazar Departamento de Medicina e Cirurgia Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brazil. https://orcid.org/0000-0002-9641-0674
  • Vivian de Assunção Nogueira Carvalho Departamento de Epidemiologia e Saúde Pública, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brazil. https://orcid.org/0000-0002-4034-9675

DOI:

https://doi.org/10.22456/1679-9216.124885

Resumo

Background: Neuroendocrine tumors are epithelial tumors with predominant neuroendocrine differentiation. A supporting treatment with furosemide, enalapril and digoxin was provided.

Case: Based on the immunohistochemical markers chromogranin and synaptophysin, the work here presented describes a case of a neuroendocrine tumor suggestive of paraganglioma involving a dog’s heart. The tumor enveloped 80% of the atria of a 9-year-old male American Bulldog.

Discussion: Treatment in question, attributed to the control of right congestive heart failure, although with little effect, denotes that the obstructive process of the return pathway, even with the use of drugs that prevent congestion, did not delay the evolution of the disease. After three months of the start of the treatment, the animal passed away.

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Referências

Brown P.J., Rema A. & Gartner F. 2003. Immunohistochemical characteristics of canine aortic and carotid Body Tumours. Journal of Veterinary Medicine. 50(1): 140-144. DOI: https://doi.org/10.1046/j.1439-0442.2003.00498.x

Capen C.C. 1998. Sistema endócrino. In: Carlton W.W. & McGavin M.D. Patologia Veterinária Especial de Thomson. 2.ed. São Paulo: Artmed, pp. 266-304.

Carvalho T.F., Coelho H.E. & Maria F. 2011. Ocorrência De Quimiodectoma em Tronco Carotídeo De Cão. PubVet. 5(31): 1-14. DOI: https://doi.org/10.22256/pubvet.v5n31.1202

Costa R.C. 2009. Neoplasias do sistema nervoso. In: Daleck C.R., De Nardi A.B. & Rodaski S. (Eds). Oncologia em Cães e Gatos. São Paulo: Roca, pp. 411-436.

Gut P., Czarnywojtek A. & Fischbach J. 2016. Chromogranin A – Unspecific neuroendocrine marker. Clinical utility and potential diagnostic pitfalls. Archives of Medicine Science. 12(1): 1-9. DOI: https://doi.org/10.5114/aoms.2016.57577

Hardcastle M.R., Meyer J. & McSporran K.D. 2015. Pathology in practice. Journal of the American Veterinary Medical Association. 247(7): 755-757. DOI: https://doi.org/10.2460/javma.247.7.755

Hays H.M. & Sass B. 1988. Chemoreceptor neoplasia: a study of the epidemiological features of 357 canine cases. Journal of Veterinary Medicine. 35(1): 401-408. DOI: https://doi.org/10.1111/j.1439-0442.1988.tb00052.x

Holscher M.A., Davis B.W. & Wilson R.B. 1986. Ectopic Thyroid Tumor in a Dog: Thyroglobulin, Calcitonin, and Neuron-Specific Enolase Immunocytochemical Studies. Veterinary Pathology. 23(1): 778-779. DOI: https://doi.org/10.1177/030098588602300619

Junqueira L.C. & Carneiro J. 2013. Histologia Básica, Texto & Atlas. 12.ed. Rio de Janeiro: Guanabara Koogan, pp.83-84.

Klimstra D.S., Modlin I.R. & Coppola D. 2010. The Pathologic Classification of Neuroendocrine Tumors: A Review of Nomenclature, Grading, and Staging Systems. Nanets Guidelines. 39(6): 767-774. DOI: https://doi.org/10.1097/MPA.0b013e3181ec124e

Le Couteur R.A. & Withrow S.J. 2007. Tumors of the nervous system. In: Withrow S.J. & Vail D.M. (Eds.) Withrow & Macewen’s Small Animal Clinical Oncology. 4th edn. St. Louis: Saunders Elsevier, pp.676-680. DOI: https://doi.org/10.1016/B978-072160558-6.50032-0

MCentee M.C. & Dewey C.W. 2013. Tumors of the nervous system. In: Withrow S.J., Vail D.M. & Page R.L. (Eds). Withrow & MacEwen’s Small Animal Clinical Oncology. 5th edn. St. Louis: Saunders Elsevier, pp.583-595. DOI: https://doi.org/10.1016/B978-1-4377-2362-5.00030-X

Meuten D.J. 2020. Tumors in Domestic Animals. 4th edn. Ames: Iowa State Press, pp. 642-696.

Morita C., Tanaka M. & Noguchi S. 2020. An aortic body carcinoma with sarcomatoid morphology and chondroid metaplasia in a French Bulldog. The Journal of Veterinary Medical Science. 82(5): 576-579. DOI: https://doi.org/10.1292/jvms.20-0016

Ramos-Vara J.A., Miller M.A., Johnson G.C. & Pace W. 2002. Immunohistochemical Detection of Thyroid Transcription Factor-1, Thyroglobulin, and Calcitonin in Canine Normal, Hyperplastic, and Neoplastic Thyroid Gland. Veterinary Pathology. 39(1): 480-487. DOI: https://doi.org/10.1354/vp.39-4-480

Rezende R.S., Eurides D. & Coelho H.E. 2018. Prevalência, Aspectos Clínicos E Anatomopatológicos de Paraganglioma de Corpo Aórtico E Carotídeo Em Cães. Arquivos de Ciências Veterinárias e Zoologia da UNIPAR. 20(3): 127-132. DOI: https://doi.org/10.25110/arqvet.v20i3.2017.6278

Stephens L.C., Sauders W.J. & Jaenke R.S. 1982. Ectopic Thyroid Carcinoma with Metastases in Beagle Dog. Veterinary Pathology. 19(1): 669-675. DOI: https://doi.org/10.1177/030098588201900612

Summers B.A., Cummings J.F. & De Lahunta A. 1995. Diseases of the peripheral nervous system. In: Summers B.A., Cummings J.F. & De Lahunta A. (Eds). Veterinary Neuropathology. St. Louis: Mosby, pp.472-501.

Yamamoto S., Fukushima R. & Hirakawa A. 2013. Histopathological and immunohistochemical evaluation of malignant potential in canine aortic body tumours. Journal of Comparative Pathology. 149(2-3): 82-191. DOI: https://doi.org/10.1016/j.jcpa.2012.12.007

Ware W.A. & Hopper D.L. 1999. Cardiac Tumors in Dogs: 1982–1995. Journal of Veterinary Internal Medicine. 13(1): 95-103. DOI: https://doi.org/10.1111/j.1939-1676.1999.tb01136.x

Walter J.H. & Rudolph R. 1996. Systemic, Metastatic, Eu- and Heterotope Tumours of the Heart in Necropsied Dogs. Journal of Veterinary Medicine. 43(1): 31-45. DOI: https://doi.org/10.1111/j.1439-0442.1996.tb00426.x

Arquivos adicionais

Publicado

2023-04-02

Como Citar

Oliveira, A. B. B. B. de ., Aben-Athar, C. do V., Filho, M. dos S., Bendas, A. J. R., Suzano, S. M. de C., Balthazar, D. de A. ., & Carvalho, V. de A. N. (2023). Tumor neuroendócrino em coração de cão: Relato de caso. Acta Scientiae Veterinariae, 51. https://doi.org/10.22456/1679-9216.124885

Edição

v. 51 (2023): CASE REPORTS (SUPPLEMENT)

Seção

Case Report

Licença

Copyright (c) 2023 Acauã Belém Barreto Batista de Oliveira, Carolina do Valle Aben-Athar, Mário dos Santos Filho, Alexandre José Rodrigues Bendas, Sara Maria de Carvalho Suzano, Daniel de Almeida Balthazar, Vivian de Assunção Nogueira Carvalho

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