Ocular Echobiometry and Resistivity Index of External Ophthalmic Artery in Agoutis (Dasyprocta prymnolopha)

Authors

  • Sabrina Barros Araújo Programa de Pós-graduação em Ciência e Saúde Animal, Universidade Federal de Campina Grande, Patos, Paraíba, Brasil https://orcid.org/0000-0001-6034-7362
  • Flávio Ribeiro Alves Departamento de Morfofisiologia Veterinária, Centro de Ciências Agrárias, Universidade Federal do Piauí (UFPI), Teresina, Piauí, Brasil https://orcid.org/0000-0002-4935-3486
  • Gerson Tavares Pessoa Programa de Pós-graduação em Ciência Animal, Universidade Federal do Piauí (UFPI) https://orcid.org/0000-0002-6285-404X
  • Renan Paraguassu de Sá Rodrigues Programa de Pós-graduação em Ciência Animal, Universidade Federal do Piauí (UFPI) https://orcid.org/0000-0002-8108-4669
  • Laecio da Silva Moura Programa de Pós-graduação em Ciência Animal, Universidade Federal do Piauí (UFPI) https://orcid.org/0000-0002-6070-2763
  • Andrezza Braga Soares da Silva Programa de Pós-graduação em Ciência Animal, Universidade Federal do Piauí (UFPI) https://orcid.org/0000-0002-6569-5515
  • Maria Angélica Parentes da Silva Barbosa Residência em Diagnóstico por Imagem, Hospital Veterinário Universitário, Universidade Federal do Piauí (UFPI), Teresina, Piauí, Brasil https://orcid.org/0000-0002-1071-1258
  • Kassio Vieira Macedo Programa de Pós-graduação em Odontologia, Universidade Federal do Piauí, Teresina, Piauí, Brasil https://orcid.org/0000-0002-9080-7267
  • Almir Pereira de Souza Programa de Pós-graduação em Ciência e Saúde Animal, Universidade Federal de Campina Grande, Patos, Paraíba, Brasil https://orcid.org/0000-0002-8587-5724

DOI:

https://doi.org/10.22456/1679-9216.117025

Abstract

Background: Veterinary Ophthalmology provides complementary information for the diagnosis of ocular pathologies. Studies in wild species are essential. Among the diagnostic techniques in ophthalmology, two-dimensional ultrasonography stands out. The agouti is a rodent belonging to the Dasyproctidae family that has been widely used as an experimental model. For these animals, sight is one of the crucial senses for their survival. The aim of this study was to evaluate the effectiveness of the two-dimensional ocular ultrasound technique to obtain anatomical measurements and the external ophthalmic artery resistivity index, presumably normal in the species Dasyprocta prymnolopha.

Materials, Methods & Results: Forty eye bulbs of 20 adult rodents of the species were evaluated by ultrasonography. In these animals, B-mode echobiometry was performed using the transpalpebral approach and the hemodynamic study of the external ophthalmic artery using the color Doppler technique. All examinations were initiated by the left eye bulb and all measurements were performed by only one examiner. The collected data related to echobiometry were analyzed using Bioest 5.0 for Windows. Initially, normality was tested using the Shapiro-Wilk test for each parameter, then the paired t-test was performed, comparing right and left eyes, and a significance level of 5% (P < 0.05) was adopted. Based on the methodology used, the following values were obtained for the right and left eyeballs, respectively: anterior chamber thickness - mean of 1.28 ± 0.3 mm and 1.22 ± 0.1 mm; lens thickness - 8.27 ± 0.9 mm and 8.11 ± 0.9 mm; vitreous chamber thickness - 5.35 ± 0.48 mm and 5.30 ± 0.47 mm and axial length - 12.7 ± 0.9 mm and 13 ± 0.68 mm. The mean external ophthalmic artery resistivity values were 0.4305 ± 0.0390 and 0.4258 ± 0.0387 (right and left eye, respectively), characterizing a low resistance. There was no statistical difference between the right and left eyeballs in any of the studied parameters.

Discussion: The use of the convex transducer was feasible, promoting adequate contact with the ocular surface and images of satisfactory quality for obtaining measurements, similar to what was observed in studies evaluating the ocular biometry of primates and dogs. The anterior chamber thickness values in this experiment did not differ statistically between the antimers, as well as observed for dogs. The data obtained for lens thickness did not differ statistically for antimers, like those obtained for other rodent species evaluated with the same methodology. The mean values of vitreous chamber thickness were like those observed in chinchillas but correspond to about half of that obtained for capybaras. In this study, the external ophthalmic artery was characterized in all animals, but obtaining the spectral tracing was difficult due to its fine caliber. In wild animals, and especially in wild rodents, there are few data reporting the resistivity of the ophthalmic artery, and there is a lack of studies, which can be explained by the behavioral characteristics of defense and by the high susceptibility to stress in capture, since the performing the technique requires, as in other procedures, the use of chemical containment.

Keywords: Doppler flow, ultrasound, eye, agouti.

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References

Araújo N.L.L.C., Raposo A.C.S., Muramoto C., Meneses D.S., Bittencourt M.V., Martins Filho E.F. & Oriá A.P. 2017. Evaluation of selected ophtalmic diagnostic tests in green iguanas (Iguana iguana). Journal of Exotic Pet Medicine. 26(3): 176-187.

Bantseev V., Oriowo O.M., Giblin F.J., Leverenz V.R., Trevithick J.R. & Sivak J.G. 2004. Effect of hyperbaric oxygen on guinea pig lens optical quality and on the refractive state of the eye. Experimental Eye Research. 78(5): 925-931.

Barathi V.A., Boopathi V.G., Yap E.P. & Beuerman R.W. 2008. Two models of experimental myopia in the mouse. Vision Research. 48(7): 904-916.

Carvalho C.F., Dupré A.S.A. & Perez R.B. 2009. Ultrassonografia Doppler ocular. In: Carvalho C.F. (Ed). Ultrassonografia Doppler em Pequenos Animais. São Paulo: Roca, pp.152-157.

Gonçalves G.F., Pippi N.L., Leme M.C., Custódio A.T., Silva A.V., Romagnolli P., Pachaly J.P., Bottin J.M.P. & Livero F.A.R. 2008. Correlação entre a pressão arterial média e o fluxo sanguíneo na artéria oftálmica externa em gatos (Fellis catus, Lineaus, 1758). Brazilian Journal of Veterinary Research and Animal Science. 45(1): 57-66.

Lima L., Montiani-Ferreira F., Tramontin M.H., Santos L.L., Machado M., Lange R.R. & Russ H.H.A. 2010. The chinchilla eye: morphologic observations, echobiometric findings and reference values for selected ophthalmic diagnostic tests. Veterinary Ophthalmology. 13(1): 14-25.

Montiani-Ferreira F., Truppel J., Tramontin M.H., Vilani R.G.D. & Lange R.R. 2008. The capybara eye: clinical tests, anatomic and biometric features. Veterinary Ophthalmology. 11(3): 386-394.

Mutti D.O., Zadnik K. & Murphy C.J. 1998. The effect of continuous light on refractive error and the ocular components of the rat. Experimental Eye Research. 67(3): 631-636.

Pachaly J.R., Monteiro Filho E.L.A., Werner P.R., Giovanelli D.F., Conti J.B., Wosiacki S.R., Belettini S.T. & Voltarelli-Pachaly E.M. 2014. Cetamina, xilazina e atropina, em doses calculadas por extrapolação alométrica interespecífica para contenção farmacológica da cutia (Dasyprocta azarae). Arquivos de Ciências Veterinárias e Zoologia. 17(1): 11-26.

Pessoa G.T., Sousa F.C.A., Rodrigues R.P.S., Moura L.S., Sanches M.P., Ambrósio C.E., Silva A.B.S. & Alves F.R. 2008. Abdominal B-mode and Doppler ultrasonography of chemically restrained agouti (Dasyprocta prymnolopha, Wagler, 1831). Pesquisa Veterinária Brasileira. 38(4): 785-793.

Renzo R. 2015. Parâmetros oftálmicos em cachorro-do-mato (Cerdocyon thous, Linnaeus, 1766). 73f. Botucatu, SP. Tese (Doutorado em Cirurgia Veterinária) - Programa de Pós-Graduação em Cirurgia Veterinária, Faculdade de Ciências Agrárias e Veterinária.

Rodas N.R. 2014. Biometria ocular ultrassonográfica e dopplerfluxometria das artérias oftálmica interna e central da retina em macaco-prego (Sapajus spp.). 93f. Botucatu, SP. Dissertação (Mestrado em Medicina Veterinária e Zootecnia) - Programa de Pós-Graduação Medicina Veterinária e Zootecnia, Faculdade de Medicina Veterinária e Zootecnia - Universidade Estadual Paulista.

Shufelt C., Fraser-Bell S., Ying-Lai M., Torres M. & Varma R. 2005. Refractive error, ocular biometry and lens opalescence in an adult population: The Los Angeles Latino eye study. Clinical and Epidemiologic Research. 46(12): 4450-4460.

Silva E.G., Pessoa G.T., Moura L.S., Guerra P.C., Rodrigues R.P.S., Sousa F.C.A., Ambrósio C.E. & Alves F.R. 2018. Biometric, B-mode and color Doppler ultrasound assessment of eyes in healthy dogs. Pesquisa Veterinária Brasileira. 38(3): 565-571.

Silva F. 1984. Mamíferos Silvestres do Rio Grande do Sul. Porto Alegre: Fundação Zoobotânica do Rio Grande do Sul, pp.171-209.

Souza L.P., Merlini N.B., Bortolini, Z., Muller T.R., Teixeira C.R., Luciani M.G., Souza D.S. & Vulcano L.C. 2018. Aspectos ultrassonográficos, biometria e dopplerfluxometria ocular do bugio ruivo (Alouatta fusca) Ultrasonography aspects, biometry and Doppler of howler monkey (Alouatta fusca). Pesquisa Veterinária Brasileira. 38(5): 1005-1013.

Squarzoni R. 2011. Biometria ocular e sua relação com sexo, idade, tamanho e peso em cães da raça Cavalier King Charles Spaniel. 96f. Botucatu, SP. Tese (Doutorado em Medicina Veterinária e Zootecnia) - Programa de Pós-Graduação em Medicina Veterinária e Zootecnia, Universidade de São Paulo.

Tramontini M.H. 2010. Contribuição ultrassonográfica na avaliação de bulbos oculares de animais domésticos e selvagens. 67f. Curitiba, PR. Dissertação (Mestrado em Ciências Veterinárias) - Programa de Pós-Graduação em Ciências Veterinárias, Universidade Federal do Paraná.

Valinhos M.A.R., Ranzani J.J.T., Rodrigues A.C.L. & Brandão C.V.S. 2012. Mensurações do bulbo ocular e cálculo do poder dióptrico de lentes intraoculares em coelhos. Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 64(1): 58-62.

Published

2021-01-01

How to Cite

Araújo, S. B., Alves, F. R., Pessoa, G. T., de Sá Rodrigues, R. P., Moura, L. da S., da Silva, A. B. S., Parentes da Silva Barbosa, M. A., Macedo, K. V., & de Souza, A. P. (2021). Ocular Echobiometry and Resistivity Index of External Ophthalmic Artery in Agoutis (Dasyprocta prymnolopha). Acta Scientiae Veterinariae, 49. https://doi.org/10.22456/1679-9216.117025

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