@article{Natalini_Polydoro_Cavalcanti_Branquinho_Crosignani_Serpa_Schallenberger_Molnar_Carregaro_Futema_2018, title={Effects of a convertible to-and-fro and circle anesthetic system on cardiopulmonary variables in isoflurane anesthetized horses}, volume={36}, url={https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/17290}, DOI={10.22456/1679-9216.17290}, abstractNote={<span style="font-family: Times New Roman; font-size: x-small;"><span style="font-family: Times New Roman; font-size: x-small;"><font face="Times New Roman" size="2"><font face="Times New Roman" size="2"><p align="left">Six healthy adult horses two male and four female, mean body weight of 424 + 44.1kg, were anesthetized with xylazine, ketamine/diazepam and isoflurane for 60 minutes using a convertible to-and-fro and circle system. Variables analyzed were arterial blood pH, carbon dioxide partial pressure (PaCO</p></font></font></span><font face="Times New Roman" size="2"><p align="left"> </p></font></span><p align="left"><span style="font-family: Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman; font-size: xx-small;">2</span></span><span style="font-family: Times New Roman; font-size: x-small;"><span style="font-family: Times New Roman; font-size: x-small;">) and oxygen partial pressure (PaO</span></span><span style="font-family: Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman; font-size: xx-small;">2</span></span><span style="font-family: Times New Roman; font-size: x-small;"><span style="font-family: Times New Roman; font-size: x-small;">), respiratory rate(RR), and blood pressure. The horses were allowed to breath spontaneously, and were positioned in right lateral recumbency. The arterial O</span></span><span style="font-family: Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman; font-size: xx-small;">2 </span></span><span style="font-family: Times New Roman; font-size: x-small;"><span style="font-family: Times New Roman; font-size: x-small;">values were significantly higher during isoflurane anesthesia when compared to the baseline values, and significantly lower after induction with ketamine/diazepam although arterial hypoxemia were not present. The arterial PCO</span></span><span style="font-family: Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman; font-size: xx-small;">2 </span></span><span style="font-family: Times New Roman; font-size: x-small;"><span style="font-family: Times New Roman; font-size: x-small;">values were significantly higher from baseline values during isoflurane anesthesia occurring arterial hypercapnia and mild respiratory<font face="Times New Roman" size="2"><font face="Times New Roman" size="2"><p align="left">acidosis. The arterial pH changes paralleled the changes in PaCO</p></font></font></span><font face="Times New Roman" size="2"><p align="left"> </p></font></span></p><p align="left"><span style="font-family: Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman; font-size: xx-small;">2</span></span><span style="font-family: Times New Roman; font-size: x-small;"><span style="font-family: Times New Roman; font-size: x-small;">. Respiratory rate values were significantly lower during </span></span><span style="font-family: Times New Roman; font-size: x-small;"><span style="font-family: Times New Roman; font-size: x-small;">isoflurane anesthesia when compared to baseline values. All values remained within accepted range for lateral recumbent spontaneously breathing anesthetized horses. There were no significant differences between the circle and the to-and-fro system, demonstrating that either system is safe to maintain isoflurane anesthesia in adult horses.</span></span></p>}, number={3}, journal={Acta Scientiae Veterinariae}, author={Natalini, Claudio Corrêa and Polydoro, Alexandre da Silva and Cavalcanti, Ruben Lundgren and Branquinho, Luciana Queiroga and Crosignani, Nadia and Serpa, Priscila Beatriz and Schallenberger, Rodrigo Gonçalves and Molnar, Bruna Favieiro Pellin de and Carregaro, Adriano and Futema, Fábio}, year={2018}, month={Mar.}, pages={229–233} }