Family History of Type 2 Diabetes is Associated with Metabolic Syndrome in Obese Female Subjects

Autores

  • Ticiana Costa Rodrigues Hospital de Clínicas de Porto Alegre
  • Luis Henrique Canani Hospital de Clínicas de Porto Alegre

Palavras-chave:

Obesity, Family history, Type 2 Diabetes, Metabolic syndrome.

Resumo

The aim of this study was to evaluate the association between the family history (FH) of type 2 diabetes and metabolic syndrome (MetS) in a group of non-diabetic obese female subjects. A cross-sectional study was conducted in 239 female patients with obesity, regularly attending the Internal Medicine Division’s outpatient clinic (Hospital de Clínicas de Porto Alegre, Brazil). The inclusion criteria were patients with body mass index ?30 kg/m2 and absence of type 2 diabetes. The FH was considered positive if a first degree relative had a diagnosis of diabetes. Seventy-four of 239 patients evaluated (30%) had a positive FH for type 2 diabetes. Patients with positive FH had higher waist/hip ratio and MetS more often than patients with negative FH. FH of type 2 diabetes was associated with MetS in this sample of non-diabetic obese female patients. Waist/hip ratio and fasting plasma glucose, markers of insulin resistance, were also associated with FH of type 2 diabetes. The simple question: “Do you have a FH of type 2 diabetes?” may help to identify the obese patients that should be better evaluated and intensively treated with the objective of preventing type 2 diabetes.

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Biografia do Autor

Ticiana Costa Rodrigues, Hospital de Clínicas de Porto Alegre

Serviço de Endocrinologia do HCPA

Luis Henrique Canani, Hospital de Clínicas de Porto Alegre

Serviço de Endocrinologia do HCPA

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Publicado

2008-08-26

Como Citar

1.
Rodrigues TC, Canani LH. Family History of Type 2 Diabetes is Associated with Metabolic Syndrome in Obese Female Subjects. Clin Biomed Res [Internet]. 26º de agosto de 2008 [citado 29º de março de 2024];28(2). Disponível em: https://seer.ufrgs.br/index.php/hcpa/article/view/3093

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