Primary Aldosteronism

Authors

  • Eduardo Guimarães Camargo Serviço de Endocrinologia, HCPA; Faculdade de Medicina, UFRGS
  • Ana Bittencourt Detanico Serviço de Endocrinologia, HCPA; Faculdade de Medicina, UFRGS
  • Renata Ortiz Pedrini Serviço de Endocrinologia, HCPA; Faculdade de Medicina, UFRGS
  • Sandra Pinho Silveiro Serviço de Endocrinologia, HCPA; Faculdade de Medicina, UFRGS

Keywords:

hiperaldosteronismo, HAP, hipocalemia, hipertensão arterial sistêmica, diabete melito, aldosterona

Abstract

Primary aldosteronism (PA) is a syndrome that results from adrenal autonomous secretion of aldosterone. The screening for this syndrome is indicated for individuals with arterial hypertension (AH) and spontaneous or severe hypocalemia after diuretics, and refractory AH (?3 antihypertensive agents). In this report, a male patient presented recent-onset diabetes mellitus (DM) and AH, weight lost, poliuria, polidipsia, and tiredness. Severe hypocalemia was present, and the laboratory workup confirmed the hypothesis of PA, with increased plasmatic and urinary aldosterone levels, low plasma renin activity and increased aldosterone/renin ratio. Adrenal computerized tomography showed a left adrenal adenoma. After the surgical procedure, blood pressure levels and glycemia were brought to normal. Though the prevalence of PA is not increased in patients with DM, it should be screened in patients with refractory AH or persistent hypocalemia. In patients with DM, cortisol metabolism should also be evaluated to rule the presence of hypercortisolism in a mixed adenoma.

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Published

2008-04-30

How to Cite

1.
Guimarães Camargo E, Bittencourt Detanico A, Ortiz Pedrini R, Pinho Silveiro S. Primary Aldosteronism. Clin Biomed Res [Internet]. 2008Apr.30 [cited 2022May23];28(1). Available from: https://seer.ufrgs.br/index.php/hcpa/article/view/2996

Issue

Section

Case Report