Reduction Glossoplasty in a Calf with Bifid Tongue

Samara de Paula Lopes, Michel Abdalla Helavel, Isabelle Magalhães de Cunha, Raphael Delecrodi, Leonardo Pereira, Syntia Dias Cerqueira, Gabriela de Carvalho Cid, Vivian de Assunção Nogueira Carvalho, Saulo Andrade Caldas

Abstract


Background: Fetal malformations are characterized by anatomical changes that compromise an organ or system. Tongue formation in bovines occurs with the fusion of three structures at the end of the fourth week of gestation, and any failure during this stage of embryonic development may lead to tongue malformation. Bifid tongue, also called glossoschisis, is a rare congenital abnormality in any species and is characterized by incomplete fusion of the lateral tongue buds, resulting in a deep groove in the midline of the tongue. The objective of this study was to describe a case of bifid tongue and the procedure of reduction glossoplasty in a calf of the Girolando breed in Tocantins State.

Case: A male mixed-breed (Holstein-Friesian × Gir) calf, born from natural mating in the municipality of Araguaína, Tocantins, was clinically assessed in the Sector of Ruminant Clinical Medicine of the Federal University of Tocantins at 2 months of age. The owner reported that the animal exhibited difficulty in suckling after birth and that on inspection of the oral cavity, he observed changes in the tongue and mandible. Clinical examination of the oral cavity revealed the presence of a bifid tongue and abnormal fusion of the mandible in the region of the lower incisive teeth. It was decided to perform a surgical procedure with the aim of improving the animal’s quality of life because the owner wanted to keep it in the farm. An incision was made, followed by removal of the medial rims of the two tines of the tongue, and synthesis was performed, joining the ventral rims of the tongue, beginning at the root and ending at the apex.

Discussion: The observed lesions are compatible with bifid tongue and mandibular fissure, both previously reported in other species. The literature has no reports of bifid tongue in bovines. The etiology of fetal malformations is still unclear, and the primary causes known in Brazil include ingestion of toxic plants by the mother, such as Mimosa tenuiflora and Poincianella pyramidalis; infections, with the main viral agents being bovine viral diarrhea virus and blue tongue virus; and teratogenic agents, namely certain medications administered during embryogenesis, e.g., ivermectin. Other potentially teratogenic agents that have not been identified as causes of malformation include radiation, cortisone, benzimidazoles, sulfonamides, folate antagonists, and organophosphates. The intense genetic improvement that the Holstein-Friesian breed has been subjected to, including inbreeding that results in consanguinity, may be a determining factor for the breed carrying mutant alleles. Because the calf in this report was crossbred from parents with Holstein-Friesian ancestry, it could carry mutant alleles that led to the malformation. Another etiology proposed in a study on embryological bases by Goodacre and Wallace (1990) is the persistence of buccopharyngeal membrane and amniotic constriction bands in the region of the branchial arches; this cause cannot be ruled out in the present case. Calves born with fetal malformations generate losses for cattle breeders because the calf dies either before or after birth, which may culminate with the death of the mother or, in cases in which the anomaly is compatible with life, damage to the animal’s development and well-being, as in the present report. Bifid tongue is a rare malformation in bovines, and reduction glossoplasty is essential for the description and improvement of techniques that aid bovine medicine; however, animals subjected to this procedure should not be used for reproduction.  


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References


Agerholm J.S., Bendixen C., Andersen O. & Arnbjerg J. 2001. Complex vertebral malformation in Holstein calves. Journal of Veterinary Diagnostic Investigation. 13(4): 283-289.

Antoniassi N.A.B., Pavarini S.P., Ribeiro L.A.O., Silva M.S., Flores E.F. & Driemeier D. 2010. Alterações clínicas e patológicas em ovinos infectados naturalmente pelo vírus da língua azul no Rio Grande do Sul. Pesquisa Veterinária Brasileira. 30(12): 1010-1016.

Ayres M.C.C. & De Almeida M.A.O. 1999. Agentes antinematódeos. In: Spinosa H. S., Gorniak S.L. & Bernardi M.M. (Eds). Farmacologia Aplicada à Veterinária. 2.ed. Rio de Janeiro: Guanabara Koogan, pp.460-463.

Correia D.A.D.B., Neto M., Gomes D.L.D.S. & Torres M.B.A.D.M. 2017. Malformações congênitas e abortos induzidos experimentalmente pela ingestão de Poincianella pyramidalis (Tul.) LP Queiroz (catingueira) em ovelhas. Pesquisa Veterinária Brasileira. 37(12): 1430-1436.

Dantas A.F.M., Riet-Correa F., Medeiros R.M.T., Galiza G.J.N., Pimentel L.A., Anjos B.L. & Mota R.A. 2010. Malformações congênitas em ruminantes no semiárido do Nordeste Brasileiro. Pesquisa Veterinária Brasileira. 30(10): 807-815.

Dezen S., Otonel R.A.A., Alfieri A.F., Lunardi M. & Alfieri A.A. 2013. Perfil da infecção pelo vírus da diarreia viral bovina (BVDV) em um rebanho bovino leiteiro de alta produção e com programa de vacinação contra o BVDV. Pesquisa Veterinária Brasileira. 33(2): 141-147.

Emmanouil-Nikoloussi E.N. & Kerameos-Foroglou C. 1992. Developmental malformations of human tongue and associated syndromes (review). Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie. 35(1-2): 5-12.

Garcia S.M.L. & Fernández C. G. 2001. Embriologia. 2.ed. Porto Alegre: Artmed, 294 p.

Goodacre T.E.E. & Wallace A.F. 1990. Congenital alveolar fusion. British Journal of Plastic Surgery. 43 (8): 203-209

Hiebert J.C., Johnson A.B., Tran H.H., Yu Z. & Glade R.S. 2016. Congenital tongue mass with concomitant cleft palate and bifid tongue: a case report and review of the literature. The Cleft Palate-Craniofacial Journal. 53(2): 245-248.

James A.W., Culver K., Hall B. & Golabi M. 2007. Bifid tongue: a rare feature associated with infants of diabetic mother syndrome. American Journal of Medical Genetics Part A. 143(17): 2035-2039.

Jolly R.D. 2002. Screening for genetic diseases in cattle. Australian Veterinary Journal. 80(5): 284-285.

Khodakaram-tafti A. & Ikede B.O. 2005. A retrospective study of sporadic bovine abortions, stillbirths, and neonatal abnormalities in Atlantic Canada, from 1990 to 2001. Canadian Veterinary Journal. 46(7): 635-637.

Lager I.A. 2004. Bluetongue virus in South America overview of viruses, vectors, surveillance and unique features. Veterinaria Italiana. 40(3): 89-93.

Leipold H.W. & Dennis S.M. 1986. Congenital defects affecting bovine reproduction. In: Morrow D.A. (Ed). Current therapy in theriogenology: diagnosis, treatment and prevention of reproductive diseases in small and large animals. Philadelphia: W.B. Saunders Company, pp.177-199.

Leipold H.W., Dennis S.M. & Huston K. 1972. Congenital defects of cattle: Nature, cause, and effect. Advances in Veterinary Science and Comparative Medicine. 16: 103-150.

Leipold H.W., Huston K. & Dennis S.M. 1983. Bovine congenital defects. Advances in Veterinary Science and comparative medicine. 27: 197-271.

Macedo J.T.S. A., Lucena R.B., Giaretta P.R., Kommers G.D., Fighera R.A., Irigoyen L.F. & Barros C.S.L. 2011. Defeitos congênitos em bovinos da Região Central do Rio Grande do Sul. Pesquisa Veterinária Brasileira. 31(4): 297-306.

Marcelino S.A.C., Macêdo J.T.S.A., Reis S.D.S., Lacerda M.S.C., Silva A.R.S., Riet-Correa F., Pimentel L.A. & Pedroso P.M.O. 2017. Malformações em pequenos ruminantes no semiárido da Bahia: aspectos epidemiológicos, clínico-patológicos e radiológicos. Pesquisa Veterinária Brasileira. 37(12): 1437-1442.

Moore K. & Persaud T.V.N. 2000. Defeitos congênitos humanos. In: Embriologia Clínica. Rio de Janeiro: Guanabara Koogan, pp.161-189.

Muir III W.W., Hubbell J.A.E., Skarda R.T. & Bednarski R.M. 2001. Fármacos usados na medicação pré-anestesica. In: Manual de Anestesia Veterinária. Porto Alegre: Artmed, pp.31-44.

Pavarini S.P., Sonne L., Antoniassi N.A.B., Santos A.S., Pescador C.A., Goberllini L.G. & Driemeier D. 2008. Anomalias congênitas em fetos bovinos abortados no sul do Brasil. Pesquisa Veterinária Brasileira. 28(3):149-154.

Pimentel L.A., Correa F.R., Gardner D., Panter K.E., Dantas A.F.M., Medeiros R. M.T. & Araújo J.A.S. 2007. Mimosa tenuiflora as a cause of malformations in ruminants in the northeastern Brazilian semiarid rangelands. Veterinary Pathology. 44(6): 928-931.

Reis S.D.S., Oliveira R.S., Marcelino S.A.C., Macêdo J.T.S.A., Riet-Correa F., Pimentel L.A. & Pedroso P.M.O. 2016. Congenital malformations and other reproductive losses in goats due to poisoning by Poincianella pyramidalis (Tul.) L.P. Queiroz (Caesalpinia pyramidalis Tul.). Toxicon. 118: 91-94.

Rifai S., Bouayad H., Kay G., Knottenbelt D.C. & Smith M. 2006. Bifid tongue and mandibular cleft in three mule foals. Veterinary Record. 158(3): 97.

Surej K.L., Kurien N.M. & Sivan M.P. 2010. Isolated congenital bifid tongue. National journal of maxillofacial surgery. 1(2): 187.

Villagomez D.A. & Alonso R.A. 1998. A distinct Mendelian autosomal recessive syndrome involving the association of anotia, palate agenesis, bifid tongue, and polydactyly in the dog. Canadian Veterinary Journal. 39(10): 642.

Whitlock B.K., Kaiser L. & Maxwell H.S. 2008. Heritable bovine fetal abnormalities. Theriogenology. 70(3): 535-549.




DOI: https://doi.org/10.22456/1679-9216.91352

Copyright (c) 2019 Samara de Paula Lopes, Michel Abdalla Helavel, Isabelle Magalhães de Cunha, Raphael Delecrodi, Leonardo Pereira, Syntia Dias Cerqueira, Gabriela de Carvalho Cid, Vivian de Assunção Nogueira Carvalho, Saulo Andrade Caldas

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